- 入驻时间: 2020-07-28
- 联系人:王珺茹
- 电话:021-54845833
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- Email:2881498548@qq.com
概 述
Full name: |
PH domain and leucine rich repeat protein phosphatase 1 |
Synonyms: |
PHLPP1 |
Swissprot: |
O60346 |
Gene Accession: |
BC014927 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. |