- 入驻时间: 2020-07-28
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别 名: ATP-binding cassette, sub-family E (OABP), member 1; RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Full name: |
ATP-binding cassette, sub-family E (OABP), member 1 |
Synonyms: |
RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI |
Swissprot: |
P61221 |
Gene Accession: |
BC016283 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. |