- 入驻时间： 2020-07-28
- 联系人：王珺茹
- 电话：021-54845833
-
联系时，请说明易展网看到的
- Email：2881498548@qq.com
储 存： 冷冻（-20℃）
概 述：
|
Full name: |
Cdc42 guanine nucleotide exchange factor (GEF) |
|
Synonyms: |
PEM2; EIEE8; PEM-2; HPEM-2; COLLYBISTIN |
|
Swissprot: |
O43307 |
|
Gene Accession: |
BC117406 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene. |
