- 入驻时间: 2020-07-28
- 联系人:王珺茹
- 电话:021-54845833
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- Email:2881498548@qq.com
Full name: |
lin-37 DREAM MuvB core complex component |
Synonyms: |
F25965; lin-37; ZK418.4 |
Swissprot: |
Q96GY3 |
Gene Accession: |
BC009071 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The LIN proteins regulate an intercellular signaling process that induces formation of the hermaphrodite vulva in C. elegans by acting to prevent the activation of a receptor tyrosine kinase/Ras signaling pathway. LIN37 is a 246 amino acid protein that is a mammalian homolog of the C. elegans Lin-37 protein. LIN37 functions as a component of the DREAM complex (also known as the LINC complex), which is comprised of several proteins, all of which work in concert to repress cell cycle-dependent genes. LIN37 is encoded by a gene located on human chromosome 19q13.2. |