商品属性：
产品名称 1号染色体开放阅读框177抗体 货号 BJ006249 英文名称 C1orf177 浓 度 1mg/ml 研究领域 细胞生物 神经生物学 细胞定位 细胞浆 抗体来源 Rabbit 性 状 Liquid 克隆类型 Polyclonal 亚 型 IgG 理论分子量 48kDa 用途 仅供科研研究实验
产品名称
1号染色体开放阅读框177抗体
货号
BJ006249
英文名称
C1orf177
浓 度
1mg/ml
研究领域
细胞生物 神经生物学
细胞定位
细胞浆
抗体来源
Rabbit
性 状
Liquid
克隆类型
Polyclonal
亚 型
IgG
理论分子量
48kDa
用途
仅供科研研究实验
商品介绍：
别 名 Chromosome 1 open reading frame 177; FLJ40201; Hypothetical protein LOC163747; Uncharacterized protein C1orf177; CA177_HUMAN. 交叉反应；(predicted: Human, Mouse, Rat, ) 产品应用；ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 免 疫 原；KLH conjugated synthetic peptide derived from human C1orf177: 21-100/414 亚 型；IgG 纯化方法；affinity purified by Protein A 缓 冲 液；0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 产品介绍： Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf177 gene product has been provisionally designated C1orf177 pending further characterization. There are two isoforms of C1orf177 that are produced as a result of alternative splicing events.
别 名 Chromosome 1 open reading frame 177; FLJ40201; Hypothetical protein LOC163747; Uncharacterized protein C1orf177; CA177_HUMAN.
交叉反应；(predicted: Human, Mouse, Rat, )
产品应用；ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
免 疫 原；KLH conjugated synthetic peptide derived from human C1orf177: 21-100/414
亚 型；IgG
纯化方法；affinity purified by Protein A
缓 冲 液；0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍：
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf177 gene product has been provisionally designated C1orf177 pending further characterization. There are two isoforms of C1orf177 that are produced as a result of alternative splicing events.
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