商品属性：
产品名称 DNA切除修复蛋白1抗体 货号 BJ007638 英文名称 ERCC1 浓 度 1mg/ml 研究领域 细胞定位 细胞核 抗体来源 Rabbit 性 状 Liquid 克隆类型 Polyclonal 亚 型 IgG 理论分子量 36kDa 用途 仅供科研研究实验
产品名称
DNA切除修复蛋白1抗体
货号
BJ007638
英文名称
ERCC1
浓 度
1mg/ml
研究领域
细胞定位
细胞核
抗体来源
Rabbit
性 状
Liquid
克隆类型
Polyclonal
亚 型
IgG
理论分子量
36kDa
用途
仅供科研研究实验
商品介绍：
别 名 Excision Repair Cross Complementing 1; DNA excision repair protein ERCC-1; COFS4; UV20; DNA excision repair protein ERCC1; ERCC 1; Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1; Excision repair protein; UV 20; UV20;DNA excision repair protein ERCC-1. 交叉反应；Human, Mouse, Rat, (predicted: Dog, Pig, Cow, ) 产品应用；WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 免 疫 原；KLH conjugated synthetic peptide derived from human ERCC1: 151-250/297 亚 型；IgG 纯化方法；affinity purified by Protein A 缓 冲 液；0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. DNA切除修复蛋白1抗体产品介绍： The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009] Subunit: Heterodimer composed of ERCC1 and XPF/ERRC4.
别 名 Excision Repair Cross Complementing 1; DNA excision repair protein ERCC-1; COFS4; UV20; DNA excision repair protein ERCC1; ERCC 1; Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1; Excision repair protein; UV 20; UV20;DNA excision repair protein ERCC-1.
交叉反应；Human, Mouse, Rat, (predicted: Dog, Pig, Cow, )
产品应用；WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
免 疫 原；KLH conjugated synthetic peptide derived from human ERCC1: 151-250/297
亚 型；IgG
纯化方法；affinity purified by Protein A
缓 冲 液；0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA切除修复蛋白1抗体产品介绍：
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009]
Subunit:
Heterodimer composed of ERCC1 and XPF/ERRC4.
单克隆抗体和多克隆抗体都是我们实验中常用的抗体产品。他们在识别的抗原表位、生产和应用等方面有一些区别。 ✓多克隆抗体（polyclonal antibody, pAb）：用一种包含多种抗原决定簇的抗原动物，可刺激机体多个 B 细胞克隆产生针对多种抗原表位的抗体。 ✓单克隆抗体（monoclonal antibodies, mAb）：由单一 B 细胞克隆产生的识别一种抗原表位的抗体。 双特异性抗体实验流程 ：
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