商品属性:
产品名称
髓样分化蛋白抗体
货号
BJ011075
英文名称
MyD88
浓 度
1mg/ml
研究领域
细胞生物 神经生物
细胞定位
细胞浆
抗体来源
Rabbit
性 状
Liquid
克隆类型
Polyclonal
亚 型
IgG
理论分子量
34kDa
用途
仅供科研研究实验
商品介绍:
别 名 myeloid differential protein-88; Myeloid differentiation primary response gene; MYD 88; MYD88D; Myeloid differentiation marker 88; Myeloid differentiation primary response gene 88; Myeloid differentiation primary response gene; Myeloid differentiation primary response protein MyD88; MYD 88; Myd88; MYD88_HUMAN; OTTHUMP; OTTHUMP; OTTHUMP; OTTHUMP; OTTHUMP.
交叉反应;Human, Mouse, Rat,
产品应用;WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
免 疫 原;KLH conjugated synthetic peptide derived from mouse MyD88: 201-296/296
亚 型;IgG
纯化方法;affinity purified by Protein A
保存条件;Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
髓样分化蛋白抗体产品介绍:
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
单克隆抗体和多克隆抗体都是我们实验中常用的抗体产品。他们在识别的抗原表位、生产和应用等方面有一些区别。 ✓多克隆抗体(polyclonal antibody, pAb):用一种包含多种抗原决定簇的抗原动物,可刺激机体多个 B 细胞克隆产生针对多种抗原表位的抗体。 ✓单克隆抗体(monoclonal antibodies, mAb):由单一 B 细胞克隆产生的识别一种抗原表位的抗体。 双特异性抗体实验流程 :
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髓样分化蛋白抗体CARM1_HUMAN; Coactivator associated arginine methyltransferase 1; Protein arginine N-methyltransferase 4; PRMT4; PRMT 4; Coactivator-associated arginine methyltransferase 1; Histone arginine methyltransferase CARM 1; Histone-arginine methyltransferase CARM1; Protein arginine methyltransferase; Protein arginine N methyltransferase 4.