商品属性:
产品名称
细胞周期调节蛋白P95抗体
货号
BJ010853
英文名称
NBN
浓 度
1mg/ml
研究领域
细胞生物 细胞周期蛋白
细胞定位
细胞核
抗体来源
Rabbit
性 状
Liquid
克隆类型
Polyclonal
亚 型
IgG
理论分子量
85kDa
用途
仅供科研研究实验
商品介绍:
别 名 p95/NBS1; p95 NBS1; Nijmegen breakage syndrome 1; Nijmegen breakage syndrome 1 (nibrin); AT V1; AT V2; AT-V1; AT-V2; ATV; Cell cycle regulatory protein p95; NBS 1; NBS; NBS1; Nibrin; Nijmegen breakage syndrome; Nijmegen breakage syndrome protein 1; p95; NBN_HUMAN; Nijmegen breakage syndrome protein 1.
交叉反应;Mouse, (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
产品应用;ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
免 疫 原;KLH conjugated synthetic peptide derived from human NBS1: 641-754/754
亚 型;IgG
纯化方法;affinity purified by Protein A
保存条件;Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞周期调节蛋白P95抗体产品介绍:
Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM,
单克隆抗体和多克隆抗体都是我们实验中常用的抗体产品。他们在识别的抗原表位、生产和应用等方面有一些区别。 ✓多克隆抗体(polyclonal antibody, pAb):用一种包含多种抗原决定簇的抗原动物,可刺激机体多个 B 细胞克隆产生针对多种抗原表位的抗体。 ✓单克隆抗体(monoclonal antibodies, mAb):由单一 B 细胞克隆产生的识别一种抗原表位的抗体。 双特异性抗体实验流程 :
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细胞周期调节蛋白P95抗体GLRA1+GLRA2; GLRA1; GLRA2; Glycine receptor 48 kDa subunit; Glycine receptor alpha 1; Glycine receptor alpha 2; Glycine receptor subunit alpha 1; Glycine receptor subunit alpha 2; Glycine receptor, alpha 1 subunit; Glycine receptor, alpha 2 subunit; STHE; GLRA1_HUMAN; GLRA2_HUMAN.