商品属性：
产品名称
腺苷单磷酸活化蛋白激酶γ2抗体
货号
BJ012428
英文名称
PRKAG2
浓 度
1mg/ml
研究领域
心血管 细胞生物 信号转导
细胞定位
细胞核 细胞浆
抗体来源
Rabbit
性 状
Liquid
克隆类型
Polyclonal
亚 型
IgG
理论分子量
63kDa
用途
仅供科研研究实验
商品介绍：
别 名 5''-AMP-activated protein kinase subunit gamma-2; AAKG; AAKG2; AAKG2_HUMAN; AMPK gamma2; AMPKgamma2; AMPK subunit gamma 2; AMPK subunit gamma-2; CMH6; H91620p; Prkag2; Protein kinase AMP activated gamma 2 non catalytic subunit; WPWS. AMPKγ2; AMPK γ2; AMPK γ 2; AMPK-γ2; AMPKγ-2; AMPK-γ-2;
交叉反应；Rat, (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, )
产品应用；WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
免 疫 原；KLH conjugated synthetic peptide derived from human PRKAG2: 265-370/569
亚 型；IgG
纯化方法；affinity purified by Protein A
保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
腺苷单磷酸活化蛋白激酶γ2抗体产品介绍：
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
单克隆抗体和多克隆抗体都是我们实验中常用的抗体产品。他们在识别的抗原表位、生产和应用等方面有一些区别。 ✓多克隆抗体（polyclonal antibody, pAb）：用一种包含多种抗原决定簇的抗原动物，可刺激机体多个 B 细胞克隆产生针对多种抗原表位的抗体。 ✓单克隆抗体（monoclonal antibodies, mAb）：由单一 B 细胞克隆产生的识别一种抗原表位的抗体。 双特异性抗体实验流程 ：
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腺苷单磷酸活化蛋白激酶γ2抗体AI593353; AW537898; CFR 1; CFR-1; CFR1; Cysteine rich fibroblast growth factor receptor; Cysteine-rich fibroblast growth factor receptor; DKFZp686L08213; E selectin ligand 1; E-selectin ligand 1; ESL 1; ESL-1; ESL1; FLJ23319; FLJ23967; FLJ32797; GLG1; Golgi apparatus protein 1; Golgi sialoglycoprotein MG 160; Golgi sialoglycoprotein MG-160; GSLG1_HUMAN; MG 160; MG160; Selel; Slectin, endothelial cell, ligand.