BDP FL tetrazine

BDP FL Tetrazine Copper free Click chemistry

Cat. #	Quantity	Price	Lead time
114E0	1 mg	110.00$	in stock
214E0	5 mg	290.00$	in stock
414E0	25 mg	690.00$	in stock
514E0	50 mg	1270.00$	in stock
614E0	100 mg	1990.00$	in stock

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Inverse electron demand Diels-Alder reaction (ied-DA) with tetrazines is a promising tool for the conjugation of biomolecules. The reaction takes place between tetrazine as an electron acceptor heterodiene, and a strained dienophile, such as trans-cyclooctene, cyclopropene, or some cyclooctynes.

Methyltetrazine provides greater stability in buffers than unsubstituted tetrazine. The rate of its reaction with cycloalkenes still beats almost all other conjugation reaction rates by a factor of magnitudes.

BDP FL is a bright dye for fluorescein (FAM) channel. Using BDP FL tetrazine, the dye can be conjugated with molecules bearing strained olefins.

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Absorption and emission spectra of BODIPY FL

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Cyanine7 tetrazine

Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.

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Tetrazine derivative of the fluorophore Cyanine3. Tetrazines react extremely quickly with strained alkenes (such as trans-cyclooctenes, cyclopropenes), and some strained alkynes.

General properties

Appearance:	red crystalline solid
Mass spec M+ increment:	447.2
Molecular weight:	475.3
Molecular formula:	C24H24N7BF2O
Solubility:	good in DCM, DMSO, DMF
Quality control:	NMR 1H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download