Pentynoic acid STP ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 30720 | 10 mg | 110.00$ | in stock | |
| 40720 | 25 mg | 210.00$ | 5 days | |
| 50720 | 50 mg | 410.00$ | in stock | |
| 60720 | 100 mg | 695.00$ | in stock |
This water soluble alkyne activated ester reagent is used for the attachment of alkyne group to variois biomolecules such as proteins, and peptides. Amino-DNA, and other amines can be used as well. Since natural proteins do not contain alkynes, but almost always contain amines (lysines), this molecule is an "adaptor" to turn natural amines into alkynes.
Use this product to enable any of your proteins for Click Chemistry.
This is an STP (sulfotetrafluorophenyl) ester. STP esters are similar to NHS esters, but possess higher hydrophilicity, and water solubility. It works fine in pure aqueous reactions without addition of organic co-solvent, and is best suited for the modification of proteins.
Recommended protocol
NHS ester labeling of amino biomolecules
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Sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for Click chemistry.General properties
| Appearance: | colorless solid |
| Mass spec M+ increment: | 80.0 |
| Molecular weight: | 348.20 |
| Molecular formula: | C11H5F4NaO5S |
| Solubility: | good in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
Product citations
- Samuelsen, S.V.; Maity, A.; Nybo, M.; Macaubas, C.; L?nstrup, L.; Balboni, I.M.; Mellins, E.D.; Astakhova, K. Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases. PLoS One, 2016, 11(6), e0156125. doi: 10.1371/journal.pone.0156125
- Maity, A.; Macaubas, C.; Mellins, E.; Astakhova, K. Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies. Molecules, 2015, 20(6), 10253–10263. doi: 10.3390/molecules200610253
