产品详情
简单介绍:
FITC - anti human BCL2 - Clone 124
详情介绍:
FITC - anti Human BCL2 - 124
Reference | Size | Price | Quantity | Add to cart |
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BCL2F-100T | 100 test |
305,00 € tax excl.
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Product Description
- 124
- IgG1
- FITC
- Please refer to the Certificate of Analysis for the lot-specific concentration.
- Synthetic peptide comprising amino acids 41-54 of human BCL2 oncoprotein
- Human
- The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
- RUO
- CD314, clone1D11, is a mAb intended for the identification of NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
- Store in the dark at 2-8 °C
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The 1D11 monoclonal antibody reacts with the human NKG2D, a 42 kDa lectin-like molecule expressed by NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.
- NKG2D
- 25 kDa
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