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  • 产品名称:PE Annexin V Apoptosis Detection Kit with 7-AAD

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  • 折扣价格:22800
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简单介绍:
PE Annexin V Apoptosis Detection Kit with 7-AAD
详情介绍:

PE Annexin V Apoptosis Detection Kit with 7-AAD

Reference Size Price Quantity Add to cart
ANXVKPE-100T 100 test
228,00 € tax excl.

Product Description

  • Flow Cytometry
  • PE
  • All mammalian
  • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
  • IVD-CE
  • Store in the dark at 2-8 °C
Annexin V Kit View larger
  • Annexin V Kit
  • Annexin V Kit

Apoptosis is characterized by a variety of morphological features. One of the earliest indications of apoptosis is the translocation of the membrane phospholipid phosphatidylserine (PS) from the inner to the outer leaflet of the plasma membrane. Once exposed to the extracellular environment, s on PS become available for Annexin V, a 35-36 kDa, Ca 2+-dependent, phospholipid binding protein with a high affinity for PS. The translocation of PS precedes other apoptotic processes such as loss of plasma membrane integrity, DNA fragmentation, and chromatin condensation. As such, Annexin V can be conjugated to biotin or to a fluorochrome, and used for the easy, flow cytometric identification of cells in the early stages of apoptosis.

Perez-Hernandez et al. Urinary dedifferentiated podocytes as a noninvasive biomarker of lupus nephritis. 2016 NEPHROLOGY DIALYSIS TRANSPLANTATION.

Cortegano I. et al.Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis. Cell Death Differ. 2014 Jul; 21(7): 1081–1094.

  • Annexin A5 
  • 308
  • 35,9 kDa
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