| Product Details | |
| Product Name | Anti-Histone H3 K27M Rabbit Monoclonal Antibody [RM192] |
| Product Description | Rabbit monoclonal to Histone H3 K27M; Histone H3, K27M Mutant |
| Catalog No. | 31-1175-00 |
| Clone Name | RM192 |
| Product Data Sheet | Anti-Histone H3 K27M Rabbit Monoclonal Antibody Data Sheet RM192 |
| Specificity | RM192 reacts to the Histone H3 K27M mutant. No cross reactivity with wild type Histone H3. |
| Immunogen | A peptide corresponding to Histone H3 K27M mutant |
| Application | Western Blot ELISA Immunohistochemistry Immunocytochemistry |
| Species Reactivity | All |
| Conjugate | None |
| Intended Use | Research Use Only |
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| Properties | |
| Form | Liquid |
| Storage Instructions | Store at -20.0°C |
| Stability | Stable for 1 Year at -20.0°C from date of receipt |
| Storage Buffer | 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Volume/Size | 50 ug |
| Concentration | 1.0 mg/mL |
| Purity | Protein A affinity purified from an animal origin–free culture supernatant |
| Clone Type | Monoclonal |
| Isotype | Rabbit IgG |
| Usage | Western Blot: 0.01 ug/mL – 1 ug/mL; ELISA: 0.5 ug/mL - 2 ug/mL; Immunohistochemistry (IHC): 0.005 – 0.1 ug/mL; Immunocytochemistry (ICC/IF): 0.005 – 0.1 ug/mL. |
| References for Histone H3 K27M Mutant antibody [RM192] | Pathania et al. H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas Cancer Cell (2017)10.1016/j.ccell.2017.09.014. IHC-P; Human. Read more (PubMed: 29107533) |
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| Product Images | |
 | Immunostaining of brain tumor tissue sections Image courtesy of Sebastian Brandner MD, Division |
 | Immunostaining of brain tumor tissue sections Image courtesy of Sebastian Brandner MD, Division |
 | Western Blot analysis of cell lysates prepared from |
 | Immunohistochemical staining of formalin fixed |
