产品详情
简单介绍：
FITC - anti human CD16 - Clone 3G8
详情介绍：
FITC - anti Human CD16 - 3G8
| Reference | Size | Price | Quantity | Add to cart |
|---|---|---|---|---|
| 16F2-100T | 100 test |
200,00 € tax excl.
|
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Product Description
- 3G8
- IgG1
- FCM
- FITC
- Please refer to the Certificate of Analysis for the lot-specific concentration.
- Human polymorphonuclear leukocytes
- Human
- The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
- IVD-CE
- CD16 clone 3G8, mAb is used for identify/enumerate human antigen (FcRIII). It′s an antipan FcγRIII (CD16) whereas clone GRM1 recognizes NA2-FcRIIIb & FcRIIIa. It′s effective for direct IF staining of human tissue for FCM tests using ≤1 μg/106 cells.
- Store in the dark at 2-8 °C
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This antibody reacts with the CD16-antigen. CD16 exists as two distinct isoforms, FcγRIIIA and FcγRIIIB. In humans, FcγRIIIA is expressed as a polypeptide-anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor. FcγRIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in non-human primates. Binding of IgG leads to activation of signal transduction pathways, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, cytokine release, and antigen presentation.
- FCRIII, Fc-gamma receptor IIIb, CD16, FCG3, FCGR3, IGFR5
- 2214
- 50-65 kDa
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