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  • 产品名称：PerCP - anti human CD16 - Clone 3G8

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简单介绍：
PerCP - anti human CD16 - Clone 3G8
详情介绍：

PerCP - anti Human CD16 - 3G8

Reference Size Price Quantity Add to cart
16PP2-100T 100 test
400,00 € tax excl.

Product Description

  • 3G8
  • IgG1
  • FCM
  • PerCP
  • Please refer to the Certificate of Analysis for the lot-specific concentration.
  • Human polymorphonuclear leukocytes
  • Human
  • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
  • RUO
  • Store in the dark at 2-8 °C
CD16 View larger
  • CD16
  • CD16

This antibody reacts with the CD16-antigen. CD16 exists as two distinct isoforms, FcγRIIIA and FcγRIIIB. In humans, FcγRIIIA is expressed as a polypeptide-anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor. FcγRIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in non-human primates. Binding of IgG leads to activation of signal transduction pathways, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, cytokine release, and antigen presentation.
  • FCRIII, Fc-gamma receptor IIIb, CD16, FCG3, FCGR3, IGFR8
  • 50-65 kDa
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