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  • 产品名称：FITC - anti human CD55 - Clone JS11

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简单介绍：
FITC - anti human CD55 - Clone JS11
详情介绍：

FITC - anti Human CD55 - JS11

Reference Size Price Quantity Add to cart
55F-100T 100 test
400,00 € tax excl.

Product Description

  • JS11
  • IgG1
  • FCM
  • FITC
  • Please refer to the Certificate of Analysis for the lot-specific concentration.
  • The immunogen was the full length version of the protein
  • Human
  • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
  • RUO
  • CD55, clone JS11 is a mAb valid for identification of DAF protein expressed on HCs including erythrocytes and many non-hematopoietic cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
CD55 View larger
  • CD55
  • CD55

This antibody reacts with the CD55-antigen (also known as DAF protein), a 41,4 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor. It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of DAF with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade . CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.
  • Decay accelerating factor, DAF, CR
  • 1604
  • 60-70 kDa
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