企业信息
第17年
  • 入驻时间： 2008-08-20
  • 联系人：客户经理
  • 电话：400-968-7988
  • 联系时，请说明易展网看到的
  • Email：fuwu@bioleaf.com
产品详情
查看大图

  • 产品名称：PE - anti human CD79a - Clone HM57

  • 产品型号：
  • 产品厂商：其它品牌
  • 产品价格：0
  • 折扣价格：26000
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
PE - anti human CD79a - Clone HM57
详情介绍：

PE - anti Human CD79a - HM57

Reference Size Price Quantity Add to cart
79APE-100T 100 test
260,00 € tax excl.

Product Description

  • HM57
  • IgG1
  • FCM
  • PE
  • Please refer to the Certificate of Analysis for the lot-specific concentration.
  • Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1.
  • Human
  • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
  • RUO
  • CD79a, clone HM57, is a mAb intended for the identification of B lymphocytes. This reagent is effective for direct iIF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
CD79a View larger
  • CD79a
  • CD79a

This antibody reacts with the CD79a-antigen. CD79a associates with CD79b to form part of the B-cell receptor complex. It has been suggested that CD79a may play a role in mediating the transport of IgM to the cell surface. This antibody has been found to react on permeabilized A20 cells (mouse B cell line). CD79a (Ig alpha, MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.
  • Mb-1, Ig?
  • 973
  • 47 kDa
标题：
内容：
联系人：
联系电话：
Email：
公司名称：
联系地址：
 
 
注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关文章

沪公网安备 31011202007337号