CF-Blue - anti Mouse Ly6 A/E - D7
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105,00 € tax excl.
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260,00 € tax excl.
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Product Description
- D7
- Rat IgG2a
- Flow Cytometry
- CF-Blue
- 0.5 mg/ml
- IL-2-dependent mouse T-cell line CTL-L
- Mouse
- The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
- RUO
- Liquid
- Store in the dark at 2-8 °C
Ly6 A/E antibody reacts with Ly6 A/E protein also known as Sca-12. It is a glycosylphosphatidylinositol (GPI)-linked protein of 18 kD expressed on hematopoietic stem cells in the bone marrow of mice with both Ly-6 haplotypes1. In mice expressing the Ly-6.2 haplotype (e.g., C57BR, AKR, C57BL, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymph ocytes and thymic and peripheral T lymph ocytes. Studies with the D7 antibody have demonstrated that Ly-6A/E may be involved in the regulation of B and T lymph ocyte responses, and it appears to be required for T-cell receptor-mediated T-cell activation
- Sca-1
- 18 kD