产品详情
简单介绍：
CAS:15966-93-5Formula:C18H18N2O3MW:310.4Appearance:YellowSolidPurity:95%
详情介绍：
A highly selective, cell-permeable indolin-2-one class of receptor tyrosine kinase (RTK) inhibitor (IC = 70 nM) for murine vascular endothelial growth factor receptor 2 (VEGF-R2; KDR/Flk-1). The inhibition is suggested to be competitive with respect to ATP. Does not inhibit PDGFR, EGFR, and IGF-1 tyrosine kinase activities (IC 100 M).
Additional Information
| Synonyms | (Z)-3-[(2,4-Dimethyl-3-(ethoxycarbonyl)pyrrol-5-yl)methylidenyl]indolin-2-one |
|---|---|
| Product # | V-1082 |
| CAS # | 15966-93-5 |
| Chemical Name | (Z)-3-[(2,4-Dimethyl-3-(ethoxycarbonyl)pyrrol-5-yl)methylidenyl]indolin-2-one |
| Formula | C18H18N2O3 |
| MW | 310.4 |
| Appearance | Yellow Solid |
| Purity | 95% |
| Solubility | Soluble in DMSO (10 mg/ml) or Etahnol (1 mg/ml) |
| Storage Temp | -20°C |
| Use | A highly selective, cell-permeable indolin-2-one class of receptor tyrosine kinase |
Additional Information
| MDL Number | MFCD04974538 |
|---|---|
| InChI | InChI=1S/C18H18N2O3/c1-4-23-18(22)16-10(2)15(19-11(16)3)9-13-12-7-5-6-8-14(12)20-17(13)21/h5-9,19H,4H2,1-3H3,(H,20,21)/b13-9- |
| SMILES | CCOC(=O)C1=C(NC(=C1C)/C=C\2/C3=CC=CC=C3NC2=O)C |
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