产品详情
简单介绍：
CAS:541503-81-5Formula:C28H38F3N5O2.C4H6O5MW:667.72Appearance:CrystallineSolidPurity:99%
详情介绍：
Second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC=0.46 nM and IC =1~10 nM to HIV isolates (n=52).
Additional Information
| Synonyms | Vicriviroc Maleate, SCH 417690, SCH-D |
|---|---|
| Product # | V-2478 |
| CAS # | 541503-81-5 |
| Chemical Name | 2-HYDROXYSUCCINIC ACID-(4,6-DIMETHYL-5-PYRIMIDINYL)(4-[(3S)-4-((1R)-2-METHOXY-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL)-3-METHYL-1-PIPERAZINYL]-4-METHYL-1-PIPERIDINYL)METHANONE |
| Formula | C28H38F3N5O2.C4H6O5 |
| MW | 667.72 |
| Appearance | Crystalline Solid |
| Purity | 99% |
| Solubility | Soluble in DMSO |
| Storage Temp | -20°C |
| Therapeutic Area | Infectious Diseases |
| Use | Vicriviroc Malate is a pyrimidine CCR5 entry inhibitor of HIV-1 |
Additional Information
| MDL Number | MFCD14635362 |
|---|---|
| ChemACX | X2768743-6 |
| InChI | InChI=1S/C28H38F3N5O2.C4H6O5/c1-19-16-35(14-15-36(19)24(17-38-5)22-6-8-23(9-7-22)28(29,30)31)27(4)10-12-34(13-11-27)26(37)25-20(2)32-18-33-21(25)3;5-2(4(8)9)1-3(6)7/h6-9,18-19,24H,10-17H2,1-5H3;2,5H,1H2,(H,6,7)(H,8,9)/t19-,24-;/m0./s1 |
| SMILES | C[C@H]1CN(CCN1[C@@H](COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C.C(C(C(=O)O)O)C(=O)O |
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