产品详情
简单介绍：
Anti-MAP2 Antibody
详情介绍：
Overview
| Name: | Anti-MAP2 Antibody See all MAP2 primary antibodies
|
| Description: | Chicken polyclonal antibody to MAP2. |
| Applications: | WB, IF/ICC, IHC |
| Dilutions: | WB: 1:20,000. IF/ICC and IHC: 1:10,000-1:20,000. |
| Reactivity: | Human, Horse, Cow, Porcine, Chicken, Rat, Mouse |
| Immunogen: | Recombinant human projection domain sequence, amino acids 377-1505. |
| Host: | Chicken |
| Clonality: | Polyclonal |
| Isotype: | IgY |
| Conjugate: | Unconjugated |
| Concentration: | 21.0 mg/ml |
| Purity: | IgY preparation. |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide. |
| Storage: | Store at 4°C. |
Target
| Function: | The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. |
| Post-Translational Modification: | Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. Isoform 3/MAP2c is probably phosphorylated by PKA at Ser-319, Ser-350 and Ser-382 and by FYN at Tyr-67. The interaction with KNDC1 enhances MAP2 threonine phosphorylation (By similarity). |
| Cellular Location: | Cytoplasm > Cytoskeleton. Cell projection > Dendrite. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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