产品详情
简单介绍：
Anti-CD3 Antibody
详情介绍：
Overview
| Name: | Anti-CD3 Antibody See all CD3 primary antibodies
|
| Description: | Mouse monoclonal (UCHT1) antibody to CD3. |
| Specificity: | The antibody UCHT1 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. The UCHT1 antibody reacts with the epsilon chain of the CD3 complex. |
| Applications: | FC, IP, IHC-Fr, FUNC |
| Reactivity: | Human, Non-Human Primates |
| Immunogen: | Human thymocytes followed by Sezary T cells. |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Clone: | UCHT1 |
| Isotype: | IgG1 |
| Conjugate: | Unconjugated |
| Purification: | Protein A chromatography. |
| Concentration: | 1 mg/ml |
| Purity: | > 95% (by SDS-PAGE) |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide. |
| Storage: | Store at 2-8°C. |
Target
| Function: | Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. |
| Involvement in Disease: | Immunodeficiency 25: An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens. |
| Sequence Similarities: | Belongs to the CD3Z/FCER1G family. |
| Post-Translational Modification: | Phosphorylated on Tyr residues after T-cell receptor triggering. |
| Cellular Location: | Membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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