产品详情
简单介绍：
Anti-CD138 Antibody
详情介绍：
Overview
| Name: | Anti-CD138 Antibody See all CD138 primary antibodies
|
| Description: | Mouse monoclonal (B-A38) antibody to CD138. |
| Specificity: | The antibody B-A38 recognizes CD138 (syndecan 1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes. |
| Applications: | FC, IHC |
| Reactivity: | Human |
| Immunogen: | U266 human peripheral blood myeloma cell line. |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Clone: | B-A38 |
| Isotype: | IgG1 |
| Conjugate: | Unconjugated |
| Purification: | Protein A chromatography. |
| Concentration: | 1 mg/ml |
| Purity: | > 95% (by SDS-PAGE) |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.4, without Azide (0.2 μm filter sterilised). |
| Storage: | Store at 2-8°C. |
Target
| Function: | Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). |
| Sequence Similarities: | Belongs to the syndecan proteoglycan family. |
| Post-Translational Modification: | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
| Cellular Location: | Membrane. Secreted. Secreted > Exosome. Shedding of the ectodomain produces a soluble form. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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