产品详情
简单介绍：
Anti-CD138 Antibody
详情介绍：
Overview
| Name: | Anti-CD138 Antibody See all CD138 primary antibodies
|
| Description: | Mouse monoclonal (B-A38) antibody to CD138. |
| Specificity: | Human CD138, Syndecan 1. |
| Applications: | IHC |
| Reactivity: | Human |
| Immunogen: | U266 cell line. |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Clone: | B-A38 |
| Isotype: | IgG1 |
| Conjugate: | Unconjugated |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.3, with Bovine Serum Albumin and 0.09% Sodium Azide. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| General Notes: | This antibody stains all plasma cells and all plasma cell lines, which have been tested so far. No other leukocytes are stained in peripheral blood or bone marrow. However, some ALL cell lines express CD138 weekly, and some epithelia and endothelia may be stained in immunohistochemistry. |
Target
| Function: | Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). |
| Sequence Similarities: | Belongs to the syndecan proteoglycan family. |
| Post-Translational Modification: | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
| Cellular Location: | Membrane. Secreted. Secreted > Exosome. Shedding of the ectodomain produces a soluble form. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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