产品详情
简单介绍：
Anti-STRO-1 Antibody
详情介绍：
Overview
| Name: | Anti-STRO-1 Antibody See all STRO-1 primary antibodies
|
| Description: | Mouse monoclonal (STRO-1) antibody to STRO-1. |
| Specificity: | The mouse monoclonal antibody STRO-1 recognizes the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors. |
| Applications: | FC, ICC |
| Reactivity: | Human |
| Immunogen: | Human CD34 positive bone marrow cells. |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Clone: | STRO-1 |
| Isotype: | IgM |
| Conjugate: | Unconjugated |
| Purification: | Purified from cell culture supernatant by precipitation and ion exchange chromatography. |
| Concentration: | 1 mg/ml |
| Purity: | > 95% (by SDS-PAGE) |
| Product Form: | Liquid |
| Formulation: | Supplied in Tris Buffered Saline, pH 8.0, with 15mM Sodium Azide. |
| Storage: | Store at 2-8°C. |
Target
| Introduction: | STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells. |
| Synonyms: |
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