产品详情
简单介绍:
Anti-Bax (C62) Antibody
详情介绍:
Target
Function: | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). |
Sequence Similarities: | Belongs to the immunoglobulin superfamily. ICAM family. |
Post-Translational Modification: | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
Cellular Location: | Membrane. |
Database Links: |
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Synonyms: | |
Information: | Target information shown above is from the UniProt Consortium. |
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