产品详情
简单介绍：
Anti-CD20 Antibody
详情介绍：
Overview
| Name: | Anti-CD20 Antibody See all CD20 primary antibodies
|
| Description: | Mouse monoclonal (L26) antibody to CD20. |
| Specificity: | Human CD20cy on peripheral and lymphoidal B-cells, germ center of lymph nodes. |
| Applications: | IHC |
| Reactivity: | Human |
| Immunogen: | B-Cells from human Tonsils. |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Clone: | L26 |
| Isotype: | IgG2a |
| Conjugate: | Unconjugated |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.3, with 0.09% Sodium Azide. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| General Notes: | This antibody reacts extremly well with B cell lymphoma, in rare cases it may also react with T cell lymphoma. In Non-Hodgkin Lymphoma Reed Sternberg Cells will be stained. |
Target
| Function: | This protein may be involved in the regulation of B-cell activation and proliferation. |
| Tissue Specificity: | Expressed on B-cells. |
| Involvement in Disease: | Immunodeficiency, common variable, 5: A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. |
| Sequence Similarities: | Belongs to the MS4A family. |
| Post-Translational Modification: | Phosphorylated. Might be functionally regulated by protein kinase(s). |
| Cellular Location: | Cell membrane. Cell membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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