产品详情
简单介绍：
Anti-CBR1 Antibody
详情介绍：
Overview
| Name: | Anti-CBR1 Antibody See all CBR1 primary antibodies
|
| Description: | Goat polyclonal antibody to CBR1. |
| Applications: | ELISA, WB, IHC |
| Reactivity: | Human |
| Immunogen: | Synthetic peptide corresponding to Human CBR1 (C terminal). |
| Sequence: | C-HGQFVSEKRVEQW |
| Host: | Goat |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 100 μg at 0.5 mg/ml. |
| Product Form: | Liquid |
| Formulation: | Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. |
| Sequence Similarities: | Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
| Cellular Location: | Cytoplasm. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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