产品详情
简单介绍：
Anti-CD73 Antibody
详情介绍：
Overview
| Name: | Anti-CD73 Antibody See all CD73 primary antibodies
|
| Description: | Mouse monoclonal (AD2) antibody to CD73. |
| Specificity: | The mouse monoclonal antibody AD2 recognizes CD73, a 70 kDa GPI-anchored 5´-nucleotidase expressed predominantly on T and B cell subsets, follicular dendritic cells and endothelial cells. |
| Applications: | FC |
| Reactivity: | Human |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Clone: | AD2 |
| Isotype: | IgG1 |
| Conjugate: | Unconjugated |
| Purification: | Protein A chromatography. |
| Concentration: | 1 mg/ml |
| Purity: | > 95% (by SDS-PAGE) |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide. |
| Storage: | Store at 2-8°C. |
Target
| Function: | Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. |
| Involvement in Disease: | Calcification of joints and arteries: A condition characterized by *****-onset calcification of the lower extremity arteries, including the iliac, femoral and tibial arteries, and hand and foot capsule joints. Age of onset has been reported as early as the second decade of life, usually involving intense joint pain or calcification in the hands. |
| Sequence Similarities: | Belongs to the 5'-nucleotidase family. |
| Cellular Location: | Cell membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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