产品详情
简单介绍：
Anti-CD13 Antibody
详情介绍：
Overview
| Name: | Anti-CD13 Antibody See all CD13 primary antibodies
|
| Description: | Mouse monoclonal (WM15) antibody to CD13. |
| Specificity: | The antibody WM15 recognises the human CD13 cell surface glycoprotein, a 150 kDa molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors. |
| Applications: | FC, IP, IHC-Fr, FUNC |
| Reactivity: | Human, Non-Human Primates |
| Immunogen: | Human AML cells. |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Clone: | WM15 |
| Isotype: | IgG1 |
| Conjugate: | Unconjugated |
| Purification: | Protein A chromatography. |
| Concentration: | 1 mg/ml |
| Purity: | > 95% (by SDS-PAGE) |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide. |
| Storage: | Store at 2-8°C. |
Target
| Function: | Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. |
| Tissue Specificity: | Expressed in epithelial cells of the kidney, intestine, and respiratory tract; granulocytes, monocytes, fibroblasts, endothelial cells, cerebral pericytes at the blood-brain barrier, synaptic membranes of cells in the CNS. Also expressed in endometrial stromal cells, but not in the endometrial glandular cells. Found in the vasculature of tissues that undergo angiogenesis and in malignant gliomas and lymph node metastases from multiple tumor types but not in blood vessels of normal tissues. A soluble form has been found in plasma. It is found to be elevated in plasma and effusions of cancer patients. |
| Sequence Similarities: | Belongs to the peptidase M1 family. |
| Post-Translational Modification: | Sulfated. |
| Cellular Location: | Cell membrane. Also found as a soluble form. |
| Database Links: |
|
| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
相关文章
