产品详情
简单介绍：
Anti-D4DR Antibody
详情介绍：
Overview
| Name: | Anti-D4DR Antibody See all D4DR primary antibodies
|
| Description: | Rabbit polyclonal antibody to D4DR |
| Specificity: | D4DR pAb detects endogenous levels of D4DR protein. |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Immunogen: | Recombinant full length Human D4DR. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Molecular Weight: | ~50 kDa |
| Purity: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Product Form: | 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol. |
Target
| Function: | Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity). |
| Sequence Similarities: | Belongs to the G-protein coupled receptor 1 family. |
| Post-Translational Modification: | Polyubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex: polyubiquitination does not lead to degradation of DRD4 protein. |
| Cellular Location: | Cell membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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