产品详情
简单介绍：
Anti-DAAM1 Antibody
详情介绍：
Overview
| Name: | Anti-DAAM1 Antibody See all DAAM1 primary antibodies
|
| Description: | Rabbit polyclonal antibody to DAAM1 |
| Specificity: | The antibody detects endogenous levels of total DAAM1 protein. |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide corresponding to a region derived from internal residues of human dishevelled associated activator of morphogenesis 1 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 3.1mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). |
| Tissue Specificity: | Expressed in all tissues examined. |
| Sequence Similarities: | Belongs to the formin homology family. |
| Cellular Location: | Cytoplasm. Cytoplasm > Cytoskeleton > Cilium basal body. Perinuclear. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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