产品详情
简单介绍：
Anti-Dact2 Antibody
详情介绍：
Overview
| Name: | Anti-Dact2 Antibody See all Dact2 primary antibodies
|
| Description: | Rabbit polyclonal antibody to Dact2 |
| Applications: | E, WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Raised against a 12 amino acid peptide from near the amino terminus of human DACT2. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Affinity chromatography purified via peptide column |
| Formulation: | Supplied in PBS containing 0.02% sodium azide. |
| Storage: | Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Target
| Function: | Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling. |
| Tissue Specificity: | Expressed in kidney (inner medullary collecting duct). Expressed in epidermal keratinocytes and hair follicles. |
| Sequence Similarities: | Belongs to the dapper family. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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