产品详情
简单介绍:
Anti-DAZ2 Antibody
详情介绍:
Overview
Name: | Anti-DAZ2 Antibody See all DAZ2 primary antibodies
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Description: | Rabbit polyclonal antibody to DAZ2 |
Applications: | WB, IF |
Dilutions: | Western blotting: 1:500-1:3000 Immunofluorescence: 1:100-1:200 |
Reactivity: | Human |
Immunogen: | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 207 of DAZ2 |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | Unconjugated |
Purification: | Purified by antigen-affinity chromatography. |
Predicted MW: | 63kd |
Formulation: | Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
Storage: | Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use. |
Target
Function: | RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. |
Tissue Specificity: | Testis specific. |
Involvement in Disease: | Spermatogenic failure Y-linked 2: A disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. |
Sequence Similarities: | Belongs to the RRM DAZ family. |
Cellular Location: | Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis. |
Database Links: |
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Synonyms: | |
Information: | Target information shown above is from the UniProt Consortium. |
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