产品详情
简单介绍：
Anti-DAZ4 Antibody
详情介绍：
Overview
| Name: | Anti-DAZ4 Antibody See all DAZ4 primary antibodies
|
| Description: | Rabbit polyclonal antibody to DAZ4 |
| Specificity: | The antibody detects endogenous levels of total DAZ4 protein. |
| Applications: | IHC |
| Reactivity: | Human |
| Immunogen: | Fusion protein corresponding to a region derived from internal residues of human Deleted in azoospermia protein 4 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 1.8mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. |
| Tissue Specificity: | Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level). |
| Involvement in Disease: | Spermatogenic failure Y-linked 2: A disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. |
| Sequence Similarities: | Belongs to the RRM DAZ family. |
| Cellular Location: | Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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