产品详情
简单介绍：
Anti-Dbf4 Antibody
详情介绍：
Overview
| Name: | Anti-Dbf4 Antibody See all Dbf4 primary antibodies
|
| Description: | Goat polyclonal antibody to Dbf4. |
| Applications: | ELISA, WB |
| Reactivity: | Mouse, Rat |
| Immunogen: | Synthetic peptide corresponding to Mouse Dbf4 (internal region). |
| Sequence: | C-DKKRTEYLPAHEDRT |
| Host: | Goat |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 100 µg at 0.5 mg/ml. |
| Product Form: | Liquid |
| Formulation: | Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role DNA in replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. |
| Cellular Location: | Nucleus. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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