产品详情
简单介绍：
Anti-DBI Antibody
详情介绍：
Overview
| Name: | Anti-DBI Antibody See all DBI primary antibodies
|
| Description: | Rabbit polyclonal antibody to DBI. |
| Applications: | WB, IHC, IF |
| Dilutions: | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200. |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human DBI. |
| Protein Length: | 87 (114) |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Affinity purification. |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. |
| Tissue Specificity: | Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. |
| Sequence Similarities: | Belongs to the ACBP family. |
| Cellular Location: | Endoplasmic reticulum. Golgi apparatus. Golgi localization is dependent on ligand binding (PubMed:17953517). |
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