产品详情
简单介绍：
Anti-DBI Antibody
详情介绍：
Overview
| Name: | Anti-DBI Antibody See all DBI primary antibodies
|
| Description: | Rabbit polyclonal antibody to DBI |
| Specificity: | DBI pAb detects endogenous levels of DBI protein. |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant full length Human DBI. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Molecular Weight: | ~10 kDa |
| Purity: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Product Form: | 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol. |
Target
| Function: | Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. |
| Tissue Specificity: | Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. |
| Sequence Similarities: | Belongs to the ACBP family. |
| Cellular Location: | Endoplasmic reticulum. Golgi apparatus. Golgi localization is dependent on ligand binding (PubMed:17953517). |
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