产品详情
简单介绍：
Anti-DGAT1 Antibody
详情介绍：
Overview
| Name: | Anti-DGAT1 Antibody See all DGAT1 primary antibodies
|
| Description: | Goat polyclonal antibody to DGAT1. |
| Applications: | ELISA, WB, IHC |
| Reactivity: | Human, Rat |
| Immunogen: | Synthetic peptide corresponding to Human DGAT1 (internal region). |
| Sequence: | C-QNSMKPFKDMDYS |
| Host: | Goat |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 100 μg at 0.5 mg/ml. |
| Product Form: | Liquid |
| Formulation: | Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. In liver, plays a role in esterifying exogenous fatty acids to glycerol. |
| Sequence Similarities: | Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily. |
| Cellular Location: | Endoplasmic reticulum membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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