产品详情
简单介绍：
Anti-Dok-6 (G130) Antibody
详情介绍：
Overview
| Name: | Anti-Dok-6 (G130) Antibody See all Dok6 primary antibodies
|
| Description: | Rabbit polyclonal antibody to Dok-6 (G130) |
| Specificity: | Dok-6 (G130) pAb detects endogenous levels of Dok-6 protein. |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide, corresponding to amino acids 98-149 of Human Dok-6. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Molecular Weight: | ~ 43 kDa |
| Purity: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Product Form: | 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Target
| Function: | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. |
| Tissue Specificity: | Highly expressed in fetal and ***** brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis. |
| Sequence Similarities: | Belongs to the DOK family. Type B subfamily. |
| Post-Translational Modification: | On Ret activation, phosphorylated on one or more C-terminal tyrosine residues by an Src family kinase. |
| Database Links: |
|
| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
相关文章
