产品详情
简单介绍：
Anti-DR1 Antibody
详情介绍：
Overview
| Name: | Anti-DR1 Antibody See all DR1 primary antibodies
|
| Description: | Rabbit polyclonal antibody to DR1. |
| Applications: | WB, IHC |
| Dilutions: | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200. |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human DR1. |
| Protein Length: | 176 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Affinity purification. |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
| Sequence Similarities: | Belongs to the NC2 beta/DR1 family. |
| Post-Translational Modification: | Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1. |
| Cellular Location: | Nucleus. |
| Database Links: |
|
| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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