产品详情
简单介绍：
Anti-DR3 Antibody
详情介绍：
Overview
| Name: | Anti-DR3 Antibody See all DR3 primary antibodies
|
| Description: | Rabbit polyclonal antibody to DR3 |
| Applications: | E, WB, ICC |
| Reactivity: | Human, Mouse |
| Immunogen: | Raised against a peptide corresponding to amino acids in extracellular domain of human DR3 precusor. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | DEAE purified |
| Formulation: | Supplied in PBS containing 0.02% sodium azide. |
| Storage: | Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Target
| Function: | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
| Tissue Specificity: | Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate. |
| Post-Translational Modification: | Glycosylated. |
| Cellular Location: | Cell membrane. |
| Database Links: |
|
| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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