产品详情
简单介绍：
Anti-DRD5 Antibody
详情介绍：
Overview
| Name: | Anti-DRD5 Antibody See all DRD5 primary antibodies
|
| Description: | Rabbit polyclonal antibody to DRD5 |
| Specificity: | The antibody detects endogenous level of total DRD5 antibody. |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human DRD5. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antibodies were purified by affinity purification using immunogen. |
| Concentration: | 1.0mg / ml |
| Formulation: | Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. |
| Tissue Specificity: | Neuron-specific, localized primarily within limbic regions of the brain. |
| Involvement in Disease: | Benign essential blepharospasm: A primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness. |
| Sequence Similarities: | Belongs to the G-protein coupled receptor 1 family. |
| Cellular Location: | Cell membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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