产品详情
简单介绍:
Anti-DSC1 Antibody
详情介绍:
Overview
Name: | Anti-DSC1 Antibody See all DSC1 primary antibodies
|
Description: | Rabbit polyclonal antibody to DSC1 |
Specificity: | The antibody detects endogenous levels of total DSC1 protein. |
Applications: | IHC |
Reactivity: | Human |
Immunogen: | Synthetic peptide corresponding to residues near the C terminal of human desmocollin 1 |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | Unconjugated |
Purification: | Antigen affinity purification. |
Concentration: | 2.8mg / ml |
Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
Storage: | Store at -20?C |
Target
Function: | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues. |
Tissue Specificity: | Strongly expressed in epidermis, less in lymph node and tongue. |
Cellular Location: | Cell membrane. Cell junction > Desmosome. |
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