产品详情
简单介绍：
Anti-DUSP16 Antibody
详情介绍：
Overview
| Name: | Anti-DUSP16 Antibody See all DUSP16 primary antibodies
|
| Description: | Goat polyclonal antibody to DUSP16. |
| Applications: | ELISA, IHC |
| Reactivity: | Human |
| Immunogen: | Synthetic peptide corresponding to Human DUSP16 (N terminal). |
| Sequence: | AHEMIGTQIVTER-C |
| Host: | Goat |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 100 μg at 0.5 mg/ml. |
| Product Form: | Liquid |
| Formulation: | Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2. |
| Sequence Similarities: | Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. |
| Post-Translational Modification: | Phosphorylated at Ser-446 by MAPK1/ERK2, which prevents its degradation, and thereby stabilizes it and blocks JNK MAPK activity. |
| Cellular Location: | Cytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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