产品详情
简单介绍：
Anti-DUSP26 Antibody
详情介绍：
Overview
| Name: | Anti-DUSP26 Antibody See all DUSP26 primary antibodies
|
| Description: | Rabbit polyclonal antibody to DUSP26 |
| Applications: | WB, IF |
| Reactivity: | Human |
| Immunogen: | Synthetic peptide contain a sequence corresponding to a region within amino acids 22 and 87 of DUSP26 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Purified by antigen-affinity chromatography. |
| Formulation: | Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
| Storage: | Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use. |
Target
| Function: | Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). |
| Tissue Specificity: | Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer. |
| Sequence Similarities: | Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. |
| Cellular Location: | Cytoplasm. Nucleus. Golgi apparatus. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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