产品详情
简单介绍：
Anti-DUSP4 Antibody
详情介绍：
Overview
| Name: | Anti-DUSP4 Antibody See all DUSP4 primary antibodies
|
| Description: | Rabbit polyclonal antibody to DUSP4 |
| Specificity: | The antibody detects endogenous level of total DUSP4 protein. |
| Applications: | E, WB, IHC |
| Dilutions: | ELISA: 1:1000-1:5000 Western blotting: 1:500-1:2000 Immunohistochemistry: 1:50-1:150 |
| Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein corresponding to a region derived from 197-394 amino acids of human dual specificity phosphatase 4 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Predicted MW: | 43kd |
| Formulation: | Supplied at 1.2mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol. |
| Storage: | Store at -20?C / 1 year |
Target
| Function: | Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. |
| Sequence Similarities: | Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. |
| Post-Translational Modification: | Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein. |
| Cellular Location: | Nucleus. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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