产品详情
简单介绍：
Anti-DYNC1I2 Antibody
详情介绍：
Overview
| Name: | Anti-DYNC1I2 Antibody See all DYNC1I2 primary antibodies
|
| Description: | Rabbit polyclonal antibody to DYNC1I2 |
| Applications: | WB, IF |
| Reactivity: | Human |
| Immunogen: | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 129 and 376 of human DYNC1I2 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Purified by antigen-affinity chromatography. |
| Formulation: | Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
| Storage: | Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use. |
Target
| Function: | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes. |
| Sequence Similarities: | Belongs to the dynein intermediate chain family. |
| Post-Translational Modification: | The phosphorylation status of Ser-90 appears to be involved in dynactin-dependent target binding. |
| Cellular Location: | Cytoplasm > Cytoskeleton. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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