产品详情
简单介绍：
Anti-ECE2 Antibody
详情介绍：
Overview
| Name: | Anti-ECE2 Antibody See all ECE2 primary antibodies
|
| Description: | Rabbit polyclonal antibody to ECE2 |
| Specificity: | The antibody detects endogenous levels of total ECE2 protein. |
| Applications: | IHC |
| Reactivity: | Human |
| Immunogen: | Fusion protein corresponding to a region derived from internal residues of human endothelin converting enzyme 2 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 1mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity. |
| Tissue Specificity: | Expressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients (at protein level). |
| Sequence Similarities: | In the N-terminal section; belongs to the methyltransferase superfamily. |
| Cellular Location: | Golgi apparatus membrane. Cytoplasmic granule membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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